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Working jointly with our sister company BGEN, we refurbished and repurposed a disused pharmaceutical production facility at AstraZeneca’s Macclesfield campus.
Refurbishing a live GMP campus asset demanded careful phasing to maintain business‑as‑usual operations while adapting an ageing building with minimal external alterations. The original production facility had high energy use (previously accounting for up to 7.5% of site energy), and significant upgrades were needed to meet modern sustainability targets. Technical constraints included delivering precise environmental control for new uses, integrating new building services alongside ongoing operations, and reconfiguring internal layouts to create collaborative, people‑centred spaces.
We planned and delivered a fully phased programme to minimise disruption, re‑imagining the layout to create a welcoming ground‑floor hub with café and breakout areas and a flexible first‑floor workspace with meeting rooms, touchdown zones and a network data hub. Sustainability guided every decision. Thermal envelope upgrades with Structural screed laid over 220 mm recycled insulation; enhanced roofing; argon‑filled glazing; and external solar shading to south elevations to cut heat loss and gain. Energy‑efficient systems with LED lighting with presence/daylight controls; low‑flow water fittings and eco‑friendly plumbing solutions; reconfiguration of HVAC and plant to optimise efficiency and recovery. A circular economy approach, which retained/repurposed foundations, steelwork, staircases, handrails, acoustic panels, partitions, and selected floor finishes to reduce waste and embodied carbon.